HIV 感染者的医疗保健利用：评估丙型肝炎病毒合并感染的负担。
Health care utilization in HIV-infected patients: assessing the burden of hepatitis C virus coinfection.
机构信息
Duke University Medical Center, Durham, North Carolina 22710, USA.
出版信息
AIDS Patient Care STDS. 2012 Sep;26(9):541-5. doi: 10.1089/apc.2012.0170. Epub 2012 Aug 3.
Abstract
Abstract Health care utilization for HIV-1-infected patients appears to be declining in the United States as a result of highly active antiviral therapy (HAART); yet the opposite appears true in the HIV/hepatitis C virus (HCV) coinfected population. The reasons for this difference are not well understood. We examined the rates and reasons for emergency department visits and hospital admissions at an academic tertiary care medical center for HIV/HCV coinfected patients as compared to HIV-1 monoinfected patients, using a retrospective matched cohort study design. HIV/HCV coinfected patients had higher rates of health care utilization (emergency department visits 43.9 versus 7.1 per 100 person-years; hospital admissions 18.2 versus 6.7 per 100 person-years, for HIV coinfected and monoinfected, respectively). This increase was not solely due to liver related events. Instead, comorbidities such as diabetes, renal disease, and psychiatric/substance abuse played a larger role in the health-care utilization in the HIV/HCV coinfected population.
摘要
摘要 由于高效抗逆转录病毒疗法（HAART）的应用，美国 HIV-1 感染者的医疗利用率似乎有所下降；然而，在 HIV/丙型肝炎病毒（HCV）合并感染者中，情况似乎正好相反。造成这种差异的原因尚不清楚。我们采用回顾性匹配队列研究设计，比较了学术三级保健医疗中心的 HIV/HCV 合并感染者和 HIV-1 单感染者因急诊就诊和住院的比率和原因。HIV/HCV 合并感染者的医疗利用率更高（急诊就诊率分别为每 100 人年 43.9 次和 7.1 次；住院率分别为每 100 人年 18.2 次和 6.7 次）。这种增加不仅仅是由于肝脏相关事件。相反，合并症如糖尿病、肾脏疾病和精神/物质滥用在 HIV/HCV 合并感染者的医疗保健利用中起着更大的作用。
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