Tropical Medicine Unit, Division of Infectious Diseases, University Health Network, Toronto, ON, Canada Division of General Internal Medicine, University Health Network, Toronto, ON, Canada Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA Division of Laboratory Medicine, Tamale Teaching Hospital, Tamale, Ghana Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.
Trop Med Int Health. 2012 Oct;17(10):1217-21. doi: 10.1111/j.1365-3156.2012.03054.x. Epub 2012 Aug 5.
To evaluate the utility of a simple questionnaire and urine reagent strip testing for the rapid diagnosis of Schistosoma haematobium in rural northern Ghana.
Cross-sectional parasitological and questionnaire survey in a community in northern Ghana. Participants provided two urine specimens that were examined under a microscope using a centrifugation method. The first urine sample was additionally subjected to reagent strip testing. A short questionnaire was administered to all participants.
Microscopy of urine samples obtained from 208 individuals aged 1-77 years revealed an S. haematobium prevalence of 6.8%. The presence of any blood or protein on a urine reagent strip was 100% and 42% sensitive, and 93% and 80% specific for S. haematobium diagnosis. Questionnaires were completed by 198 individuals. Self-reported haematuria showed a sensitivity of 53% and a specificity of 85%. A dichotomous two-question panel was helpful in S. haematobium diagnosis, with working and playing near the river significantly associated with S. haematobium infection (P < 0.001).
The use of urine reagent strips, coupled with questions pertaining to water contact patterns, might be considered for point-of-contact diagnosis of S. haematobium where microscopy is unavailable.
评估一种简单的问卷和尿液试剂条检测方法在加纳北部农村快速诊断埃及血吸虫病的效用。
在加纳北部的一个社区进行横断面寄生虫学和问卷调查。参与者提供了两份尿液样本，用离心法在显微镜下检查。第一份尿液样本还进行了试剂带检测。对所有参与者进行了简短的问卷调查。
对 208 名年龄在 1 至 77 岁的个体的尿液样本进行显微镜检查，发现埃及血吸虫病的患病率为 6.8%。尿液试剂带检测到任何血液或蛋白质的敏感性为 100%和 42%，特异性为 93%和 80%。198 名个体完成了问卷。自我报告的血尿敏感性为 53%，特异性为 85%。两个问题的二分面板有助于埃及血吸虫病的诊断，在河边工作和玩耍与埃及血吸虫病感染显著相关（P < 0.001）。
在没有显微镜的情况下，尿液试剂带结合与水接触模式相关的问题，可能可以考虑用于埃及血吸虫病的现场诊断。
