Schwaiger S, Breitbach G P, Bruch P M, Tkocz H P, Schmidt W
Universitäts-Frauenklinik und Poliklinik Homburg/Saar.
Geburtshilfe Frauenheilkd. 1990 Oct;50(10):816-8. doi: 10.1055/s-2008-1026371.
Between 1985 and 1989, four patients with uvea metastases of breast cancers were treated in the Dept. of Gynaecology and Obstetrics of the University of the Saar, Medical School, in Homburg/Saar. One of these patients developed binocular metastases. The patient's age at the primary diagnosis of breast cancer was 48 years (median), the others were in pre- or peri-menopausal status. Uvea metastases appeared in median five years after primary diagnosis, always in coincidence with at least one more metastasis of different localisation. All cases with uvea metastases have been treated by radiation therapy with 40 gy reference dose. In three out of five cases, complete remission of the visus restriction could be achieved. In a further case, a temporary partial remission occurred. Two relapses were observed after remission induction, one and four years after treatment respectively.
1985年至1989年间,萨尔大学医学院洪堡/萨尔分校妇产科收治了4例患有乳腺癌葡萄膜转移的患者。其中1例患者出现双眼转移。乳腺癌初诊时患者的年龄中位数为48岁,其他患者处于绝经前或围绝经期状态。葡萄膜转移出现于初诊后的中位数5年,且总是与至少一处其他部位的转移同时出现。所有葡萄膜转移病例均接受了参考剂量为40戈瑞的放射治疗。5例中有3例实现了视力受限的完全缓解。在另一例中,出现了暂时的部分缓解。缓解诱导后观察到2例复发,分别在治疗后1年和4年。