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下颌部高分化非转移纤维肉瘤(侵袭性纤维瘤病):一例罕见病例报告及文献复习。

Well differentiated nonmetastasizing fibrosarcoma (aggressive fibromatosis) of mandible: a rare case report and a literature review.

机构信息

Department of Oral and Maxillofacial Surgery, CSMSS Dental College, Aurangabad, India.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Aug;116(2):e98-102. doi: 10.1016/j.oooo.2011.12.015. Epub 2012 Aug 3.

DOI:10.1016/j.oooo.2011.12.015
PMID:22863606
Abstract

Fibromatosis in the maxillofacial region is a very rare occurrence among diverse pathologic conditions, and because of the rarity of this tumor, definite treatment regimen is not established, which may be a contributing factor for a high recurrence rate. Fibromatosis may attain a large size and cause compression, infiltration, and destruction of adjacent structures. Such growth behavior presents severe management problems, especially in the head and neck region, where the presence of many vital structures within a small space makes the patient susceptible to the effects of the fibromatosis, likewise making complete excision difficult. We report the case of a 28-year-old female patient with aggressive desmoid fibromatosis involving the mandible, with a literature review of postoperative pharmacologic management to prevent recurrence.

摘要

颌面部纤维瘤病在各种病理情况下非常罕见,由于这种肿瘤罕见,因此尚未确定明确的治疗方案,这可能是高复发率的一个因素。纤维瘤病可能会增大,并导致对邻近结构的压迫、浸润和破坏。这种生长行为会带来严重的管理问题,特别是在头部和颈部区域,由于许多重要结构位于狭小的空间内,患者容易受到纤维瘤病的影响,同样也使得完全切除变得困难。我们报告了一例 28 岁女性患者的侵袭性硬纤维瘤病累及下颌骨的病例,并对术后预防复发的药物治疗进行了文献回顾。

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Well differentiated nonmetastasizing fibrosarcoma (aggressive fibromatosis) of mandible: a rare case report and a literature review.下颌部高分化非转移纤维肉瘤(侵袭性纤维瘤病):一例罕见病例报告及文献复习。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Aug;116(2):e98-102. doi: 10.1016/j.oooo.2011.12.015. Epub 2012 Aug 3.
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引用本文的文献

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Mandibular versus Maxillary Desmoplastic Fibroma: A Pooled Analysis of World Literature and Report of a New Case.下颌骨与上颌骨促结缔组织增生性纤维瘤:世界文献的汇总分析及1例新病例报告
Eur J Dent. 2025 Jul;19(3):595-606. doi: 10.1055/s-0044-1801277. Epub 2025 Mar 12.
2
Aggressive fibromatosis of the oral cavity in a 5 year old boy: a rare case report.一名5岁男孩口腔侵袭性纤维瘤病:罕见病例报告
Pan Afr Med J. 2017 May 18;27:47. doi: 10.11604/pamj.2017.27.47.11739. eCollection 2017.