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尼泊尔一家社区医院翼状胬肉手术中结膜自体移植的结果

Outcome of conjunctival autograft transplantation in pterygium surgery in a community based hospital in Nepal.

作者信息

Sharma R, Marasini S, Nepal B P

机构信息

Department of Ophthalmology, Kathmandu University Hospital, Dhulikhel, Nepal.

出版信息

Nepal J Ophthalmol. 2012 Jul-Dec;4(2):242-7. doi: 10.3126/nepjoph.v4i2.6539.

DOI:10.3126/nepjoph.v4i2.6539
PMID:22864029
Abstract

INTRODUCTION

The mainstay of treatment for pterygium is surgical excision with or without a graft. The most common problem with this intervention is recurrence, for which a multitude of factors have been described.

OBJECTIVE

To evaluate the recurrence rate of pterygium in conjunctival autologous graft transplantation after its excision in people living in a hilly region of Nepal Materials and methods: A prospective interventional study was conducted in patients undergoing pterygium excision with conjunctival autologous graft transplantation. The patients were followed up for 20 months. Any recurrence of pterygium was noted during this period.

RESULTS

Thirty four patients with an age range of 29 to 65 years (mean 43.88+/-9.19 years) were included. Female predominated (n=21, 61.8%) in the study. Service holders formed a majority of the cases (n=14, 41.2%) followed by farmers (n=10, 29.4%, OR 0.019, 95% CI = 0.002 to 0.209). Ocular discomfort was the main presenting complaint. Dry eye was seen in 30 patients (88.23%). Most of the patients (26, 76.5%) had a grade II pterygium. Graft displacement was the main complication in two (5.88%) patients and recurrence of pterygium was found in three (8.82%).

CONCLUSION

Conjunctival autologous transplantation is a safe and effective method for the treatment of pterygium with a minimal recurrence rate.

摘要

引言

翼状胬肉的主要治疗方法是手术切除,可选择或不选择移植。这种干预最常见的问题是复发,对此已有多种因素被描述。

目的

评估尼泊尔山区居民翼状胬肉切除术后结膜自体移植的复发率。材料与方法:对接受翼状胬肉切除联合结膜自体移植的患者进行前瞻性干预研究。对患者进行了20个月的随访。在此期间记录翼状胬肉的任何复发情况。

结果

纳入了34例年龄在29至65岁(平均43.88±9.19岁)的患者。研究中女性占主导(n = 21,61.8%)。服务人员占大多数病例(n = 14,41.2%),其次是农民(n = 10,29.4%,OR 0.019,95% CI = 0.002至0.209)。眼部不适是主要的就诊主诉。30例患者(88.23%)出现干眼。大多数患者(26例,76.5%)患有二级翼状胬肉。两名患者(5.88%)出现移植片移位,三名患者(8.82%)发现翼状胬肉复发。

结论

结膜自体移植是一种治疗翼状胬肉的安全有效方法,复发率极低。

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