Epigenetics. 2012 Aug;7(8):965. doi: 10.4161/epi.21623. Epub 2012 Aug 1.
We are responding to a Letter to the Editor addressing the Method section of our paper “Different measures of ‘genome-wide’ DNA methylation exhibit unique properties in placental and somatic tissues.” The letter raised concerns that the protocol for Epigentek’s MethylFlash kit was followed incorrectly based on the wording of an online publication of our article. We admittedly made an error in the language used to describe the MethylFlash protocol in our initial submission and thus this was corrected as soon as it was brought to our attention. However, the error was only in language and not procedure. We are confident that the protocol was followed as stated in the insert provided with the MethylFlash Methylated DNA Quantification kit (Colorimetric).
我们正在回复一封针对我们论文“‘全基因组’DNA 甲基化的不同测量方法在胎盘和体细胞组织中表现出独特的性质”的方法部分的编辑信函。这封信提出了一个担忧，即根据我们文章的在线出版物的措辞，错误地遵循了 Epigentek 的 MethylFlash 试剂盒的方案。我们承认，在我们最初提交的论文中，我们在描述 MethylFlash 方案的语言上犯了一个错误，因此，一旦我们注意到这个问题，就立即进行了纠正。然而，这个错误只是在语言上，而不是在程序上。我们有信心，该方案是按照 MethylFlash 甲基化 DNA 定量试剂盒（比色法）中提供的插页中所述进行的。
