Moulay Ismail University, Errachidia, Morocco.
Clin Exp Hypertens. 2013;35(3):200-6. doi: 10.3109/10641963.2012.712179. Epub 2012 Aug 6.
This study aims to evaluate the in vitro vasorelaxant effect of C. nobile aqueous extract. We use aortic ring isolated from Wistar rats and aqueous C. nobile extract at doses of 5, 10 and 20 mg/ml. Incubation of aqueous C. nobile extract for 30 minutes produced a significant shift of the dose-response curve to norepinephrine (NE) (10(-8) to 10(-5) M) (p < 0.001). This study demonstrates that aqueous C. nobile extract possesses in vitro vasorelaxant effect.
本研究旨在评估 C. nobile 水提物的体外血管舒张作用。我们使用 Wistar 大鼠的主动脉环和浓度为 5、10 和 20mg/ml 的 C. nobile 水提物进行实验。水提 C. nobile 提取物孵育 30 分钟可使去甲肾上腺素（NE）（10(-8) 至 10(-5) M）的剂量-反应曲线显著移动（p < 0.001）。本研究表明，C. nobile 水提物具有体外血管舒张作用。
