Seikel J A, Wilcox K A, Davis J
Department of Speech and Hearing Sciences, Washington State University, Pullman 99164-2420.
J Commun Disord. 1990 Dec;23(6):417-31. doi: 10.1016/0021-9924(90)90028-w.
Motor Neuron Disease (MND) is a terminal, demyelinating disease affecting upper- and lower-motor neurons and producing muscular weakness resulting in a characteristic spastic-flaccid dysarthria of speech. The present study investigates the relationship between the temporal-acoustic parameters of the speech of 15 individuals with MND as they relate to the progression of the disease and clinicians' judgments of dysarthria severity. When temporal-acoustic parameters are used to predict the progression of MND, it becomes apparent that victims provide compensatory gestures to mark voicing distinctions. When the same acoustic parameters are used to predict clinician judgments of severity, it is found that clinicians tend to use the same temporal cues that mark actual disease progression. Differences between the two sets of predictions relate to the linguistic systems of both speaker and judge, and the implications of this are discussed.
运动神经元病（MND）是一种晚期脱髓鞘疾病，影响上下运动神经元，导致肌肉无力，进而产生特征性的痉挛性-弛缓性言语障碍。本研究调查了15名运动神经元病患者的言语时间声学参数与疾病进展以及临床医生对构音障碍严重程度的判断之间的关系。当使用时间声学参数来预测运动神经元病的进展时，很明显患者会做出补偿性手势来标记语音差异。当使用相同的声学参数来预测临床医生对严重程度的判断时，发现临床医生倾向于使用与实际疾病进展相关的相同时间线索。两组预测之间的差异与说话者和判断者的语言系统有关，并对此进行了讨论。
