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对一例亲子关系案件中DNA多位点图谱的分析,该案件中孩子的图谱可能不完整。

Analysis of DNA multilocus profiles in a paternity case in which the child's profile may be partial.

作者信息

Evett I W

机构信息

Central Research and Support Establishment, Home Office Forensic Science Service, Reading, Berkshire, United Kingdom.

出版信息

J Forensic Sci Soc. 1990 Sep-Oct;30(5):293-7. doi: 10.1016/s0015-7368(90)73357-9.

Abstract

This report describes a simple approach to multilocus paternity analysis for cases where the child's sample may be inadequate leading to a partial profile. A specimen calculation is given. A previous paper described how the various band sharing configurations in the DNA multilocus profiles of a mother-child-putative father trio could be combined in a comprehensive mathematical analysis to give an overall Bayesian likelihood ratio. In that paper, it was assumed that all three members of the trio gave full DNA profiles. In some cases that assumption may not be valid but it is possible to extend the analysis to allow for partial profiles. This paper demonstrates how this may be done by considering the case where the child's profile may be partial for one reason or another. A specimen calculation is given.

摘要

本报告描述了一种简单的多位点亲权分析方法,适用于儿童样本可能不足而导致部分图谱的情况。文中给出了一个示例计算。之前的一篇论文描述了如何将母子-推定父亲三联体的DNA多位点图谱中的各种条带共享配置组合到一个全面的数学分析中,以得出一个整体的贝叶斯似然比。在那篇论文中,假设三联体的所有三个成员都给出了完整的DNA图谱。在某些情况下,该假设可能不成立,但可以扩展分析以考虑部分图谱的情况。本文通过考虑儿童图谱可能因某种原因而部分缺失的情况,演示了如何做到这一点。文中给出了一个示例计算。

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