Sakaguchi T
Department of Cardiovascular Surgery, Osaka University School of Medicine, Suita, Japan.
Kyobu Geka. 2012 Jul;65(8):648-52.
Severe atherosclerosis of the ascending aorta frequently causes difficulties during heart operations, hindering surgical maneuvers and potentially leading to systemic embolism. There have been several methods to solve these problems but the best way to treat patients requiring aortic valve replacement (AVR) has not been established yet. Surgical techniques for AVR in these patients include AVR under deep hypothermic circulatory arrest with or without endarterectomy of the ascending aorta or replacement of the ascending aorta. Endovascular clamping using a balloon is another approach but requires manipulation of the heavily calcified aorta that may result in a certain risk for stroke. Another option to avoid the ascending aorta and cross-clamping is the apicoaortic conduit. Recently introduced trans-catheter AVR (TAVR), especially trans-apical AVR, has been shown to be feasible in such patients. Larger studies and longer follow-up will be required to scientifically prove the superiority of trans-apical AVR over conventional surgical strategies in patients with porcelain aorta requiring AVR.
升主动脉严重动脉粥样硬化常给心脏手术带来困难,阻碍手术操作,并可能导致全身栓塞。已有多种方法来解决这些问题,但治疗需要主动脉瓣置换(AVR)患者的最佳方法尚未确定。这些患者的AVR手术技术包括在深低温循环停搏下进行AVR,同时或不进行升主动脉内膜切除术或升主动脉置换术。使用球囊进行血管内钳夹是另一种方法,但需要对严重钙化的主动脉进行操作,这可能导致一定的中风风险。另一种避免升主动脉和交叉钳夹的选择是心尖主动脉导管。最近引入的经导管AVR(TAVR),尤其是经心尖AVR,已被证明在此类患者中是可行的。需要更大规模的研究和更长时间的随访,以科学地证明在需要AVR的瓷化主动脉患者中,经心尖AVR优于传统手术策略。