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类固醇在减少鼻整形术后水肿中的作用:一项荟萃分析研究。

Role of steroids in reducing postoperative edema in rhinoplasty: a meta-analytic study.

机构信息

Ain Shams University, Cairo, Egypt.

出版信息

Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1189-93. doi: 10.1007/s00405-012-2144-y. Epub 2012 Aug 9.

Abstract

The study aimed at verifying the use of steroids to decrease postoperative edema after rhinoplasty. The study included published articles yielded by the Medline database search concerning role of steroids in rhinoplasty. The search was limited to articles published in English in the last three decades. The search was done on 1/2/2012. For the 15 relevant articles, we applied our inclusion and exclusion criteria and only four articles were included. The data collected from each article were statistically analyzed utilizing meta-analytic Review manager (RevMan 5.1) software (Version: 5.1.0.0). Perioperative steroid use significantly reduces postoperative edema of the upper and lower eyelids on the first and third days postoperative, with no significant effect after third day. The results indicated that steroids should be given for patients undergoing rhinoplasty for decreasing periorbital edema postoperatively especially in the first 3 days, however, it has little effect after the third day.

摘要

本研究旨在验证类固醇在鼻整形术后减少术后水肿的应用。研究包括通过 Medline 数据库搜索获得的关于类固醇在鼻整形术中作用的已发表文章。搜索仅限于过去三十年中以英文发表的文章。搜索于 2012 年 2 月 1 日进行。对于 15 篇相关文章,我们应用了纳入和排除标准,仅纳入了 4 篇文章。从每篇文章中收集的数据利用 meta 分析 Review manager(RevMan 5.1)软件(版本:5.1.0.0)进行了统计分析。围手术期使用类固醇可显著减少术后第 1 天和第 3 天上、下眼睑的术后水肿,第 3 天以后无显著影响。结果表明,类固醇应该给予接受鼻整形术的患者,以减少术后眶周水肿,特别是在前 3 天,但第 3 天以后效果较小。

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