Manzi S V, Hager K H, Murtagh F R, Mazalewski J G
Department of Radiology, University of South Florida, College of Medicine, Tampa.
Pediatr Radiol. 1990;21(1):62-3. doi: 10.1007/BF02010818.
Leigh's disease, also known as subacute necrotizing encephalomyelopathy, is a rare progressive neurological disorder of childhood that was first described by Leigh in 1951. Diagnosis of this disease can be difficult because onset is usually insidious and can present with a number of different focal findings, however diagnostic imaging has been shown to be of benefit in this regard. We present a patient with Leigh's disease in whom serial MR imaging studies helped to make the diagnosis and also demonstrated the dynamic characteristic of this disease process.
