人胰岛素与动物胰岛素使用者低血糖风险的比较。1. 英国的经验。
A comparison of the risk of hypoglycemia between users of human and animal insulins. 1. Experience in the United Kingdom.
作者信息
Jick H, Hall G C, Dean A D, Jick S S, Derby L E
机构信息
Boston Collaborative Drug Surveillance Program, Boston University Medical Center, Waltham, Massachusetts 02154.
出版信息
Pharmacotherapy. 1990;10(6):395-7.
In a case-control study of 121 young insulin-dependent diabetics diagnosed as having an episode of hypoglycemia, the relative risk estimate comparing human with animal insulins was 0.8 (95% confidence interval 0.4, 1.6) controlling for age, general practice, and calendar time. We conclude that in this study population derived from general practices in the United Kingdom, the risk of hypoglycemia was no higher in users of human insulin than it was in users of animal insulins.
在一项针对121名被诊断为有低血糖发作的年轻胰岛素依赖型糖尿病患者的病例对照研究中，在控制年龄、全科医疗和日历时间的情况下，比较人胰岛素与动物胰岛素的相对风险估计值为0.8（95%置信区间为0.4, 1.6）。我们得出结论，在这项源自英国全科医疗的研究人群中，使用人胰岛素的患者发生低血糖的风险并不高于使用动物胰岛素的患者。
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