Department of Surgical Oncology, Erasmus MC, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Ann Surg Oncol. 2013 Jan;20(1):155-60. doi: 10.1245/s10434-012-2537-6. Epub 2012 Aug 9.
There is no evidence regarding restaging of patients with locally advanced rectal cancer after a long course of neoadjuvant radiotherapy with or without chemotherapy. This study evaluated the value of restaging with chest and abdominal computed tomographic (CT) scan after radiotherapy.
Between January 2000 and December 2010, all newly diagnosed patients in our tertiary referral hospital, who underwent a long course of radiotherapy for locally advanced rectal cancer, were analyzed. Patients were only included if they had chest and abdominal imaging before and after radiotherapy treatment.
A total of 153 patients who met the inclusion criteria and were treated with curative intent were included. A change in treatment strategy due to new findings on the CT scan after radiotherapy was observed in 18 (12%) of 153 patients. Twelve patients (8%) were spared rectal surgery due to progressive metastatic disease.
Restaging with a chest and abdominal CT scan after radiotherapy for locally advanced rectal cancer is advisable because additional findings may alter the treatment strategy.
对于接受长程新辅助放化疗或单纯放疗的局部晚期直肠癌患者，目前尚无关于其后续再分期的证据。本研究旨在评估放疗后行胸部和腹部 CT 扫描再分期的价值。
在 2000 年 1 月至 2010 年 12 月期间，对在我院接受长程放疗的所有新诊断局部晚期直肠癌患者进行了分析。只有在放疗前后均行胸部和腹部影像学检查的患者才被纳入。
共纳入了 153 例符合纳入标准且接受根治性治疗的患者。在这 153 例患者中，有 18 例（12%）因放疗后 CT 扫描的新发现而改变了治疗策略。由于进展性转移疾病，12 例患者（8%）避免了直肠手术。
对于局部晚期直肠癌患者，在放疗后行胸部和腹部 CT 扫描再分期是合理的，因为额外的发现可能会改变治疗策略。
