Dissado L A
Department of Physics, King's College London, UK.
Phys Med Biol. 1990 Nov;35(11):1487-503. doi: 10.1088/0031-9155/35/11/005.
An improvement to Schwan's model of the dielectric response of biological tissues is proposed which is based on a fractal interpretation of the power law behaviour (epsilon' alpha epsilon" alpha f"-1) often observed. This interpretation allows the response to be more specifically related to the sub-cellular and cellular organization of the tissue through its self-similar hierarchical nature. A number of examples are discussed ranging in tissue type from the mostly cellular liver tissue to nerve tissue (grey matter). Applications of the technique to diseased and damaged tissue are briefly touched upon so as to illustrate its potential for precisely defining their effect upon the cells' electrical behaviour at a specific organizational level.
提出了对施万生物组织介电响应模型的一种改进,该改进基于对常观察到的幂律行为(ε'∝ε''∝f⁻¹)的分形解释。这种解释通过组织的自相似层次性质,使响应能更具体地与组织的亚细胞和细胞结构相关联。讨论了许多例子,组织类型从主要是细胞的肝组织到神经组织(灰质)。简要提及了该技术在患病和受损组织上的应用,以说明其在特定组织水平精确界定它们对细胞电行为影响的潜力。