Li Min, Yang Ming-Hui, Liu Yi
Department of Traditional Chinese Medicine, General Hospital of Chinese PLA, Beijing 100853, China.
Zhong Yao Cai. 2012 Mar;35(3):503-6.
To study the effects of "Attenuation and Synergia" for Bushenhuoxue Granules (BSHXG) on Parkinson's patients.
120 patients were enrolled and divided into two groups randomly, the control group were treated with placebo and treatment group with BSHXG, both groups based on Madopar treatment. Double-blinded clinical trial was adopted in treatment period. Follow-up period for 6 months. Usage of Madopar and score of treatment complications were adopted to measure related motor complications before and after treatment.
Usage of Madopar and score of treatment complications in treatment group were decreased (P < 0.05). No adverse effects were found in this trial.
BSHXG can decrease the side-effects of Madopar and put off the development of PD. The effects of "Attenuation and Synergia" of BSHXG becomes clear with time.
研究补肾活血颗粒“减毒增效”对帕金森病患者的影响。
纳入120例患者，随机分为两组，对照组服用安慰剂，治疗组服用补肾活血颗粒，两组均基于美多芭治疗。治疗期间采用双盲临床试验。随访6个月。采用美多芭用量及治疗并发症评分来衡量治疗前后相关运动并发症。
治疗组美多芭用量及治疗并发症评分降低（P<0.05）。本试验未发现不良反应。
补肾活血颗粒可降低美多芭的副作用，延缓帕金森病的发展。补肾活血颗粒“减毒增效”作用随时间推移而显现。
