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[微粒体细胞色素的电化学分析]

[Electrochemical analysis of microsomal cytochromes].

作者信息

Kuznetsov B A, Mestechkina N M, Izotov M V, Karuzina I I, Kariakin A V

出版信息

Biokhimiia. 1979 Sep;44(9):1569-75.

PMID:228771
Abstract

The electrochemical behaviour of the electron transfer proteins -- cytochromes b5, c and P-450 was studied by classical polarography and electrolysis with spectrophotometric monitoring. It was shown electrons are directly transferred from the electrode to oxidized cytochromes c and b5. Cytochrome P-450 is not reduced on the electrodes. However, the reduced inactivated from of cytochrome P-420 was detected at high potential values (-1,5 v).

摘要

通过经典极谱法和带有分光光度监测的电解法研究了电子传递蛋白——细胞色素b5、c和P - 450的电化学行为。结果表明,电子可直接从电极转移至氧化态的细胞色素c和b5。细胞色素P - 450在电极上不会被还原。然而,在高电位值(-1.5伏)时检测到了细胞色素P - 420的还原失活形式。

相似文献

1
[Electrochemical analysis of microsomal cytochromes].[微粒体细胞色素的电化学分析]
Biokhimiia. 1979 Sep;44(9):1569-75.
2
Electrochemical measurement of second-order electron transfer rate constants for the reaction between cytochrome b5 and cytochrome c.细胞色素b5与细胞色素c之间反应的二阶电子转移速率常数的电化学测量。
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Examination of extinction coefficients of soluble and membrane-bound cytochromes P-450 and P-420.可溶性和膜结合细胞色素P-450及P-420的消光系数检测
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Differences in the mechanism of functional interaction between NADPH-cytochrome P-450 reductase and its redox partners.NADPH-细胞色素P-450还原酶与其氧化还原伙伴之间功能相互作用机制的差异。
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[Oxidation of cytochrome b5 reduced by ascorbic acid].[被抗坏血酸还原的细胞色素b5的氧化作用]
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The role of oxygenated cytochrome P-450 and of cytochrome b5 in hepatic microsomal drug oxidations.氧化型细胞色素P-450和细胞色素b5在肝微粒体药物氧化中的作用。
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Arch Biochem Biophys. 1996 Jan 15;325(2):174-82. doi: 10.1006/abbi.1996.0022.
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