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重度硝基咪唑类药物过敏情况下的有症状阴道毛滴虫感染:硼酸治疗成功案例

Symptomatic Trichomonas vaginalis infection in the setting of severe nitroimidazole allergy: successful treatment with boric acid.

作者信息

Muzny Christina, Barnes Arti, Mena Leandro

机构信息

Division of Infectious Diseases, University of Alabama, Birmingham, AL 35294, USA.

出版信息

Sex Health. 2012 Sep;9(4):389-91. doi: 10.1071/SH11114.

DOI:10.1071/SH11114
PMID:22877600
Abstract

This report describes a patient with symptomatic Trichomonas vaginalis infection who was unable to tolerate nitroimidazole drugs because of severe hypersensitivity, for which desensitisation was not possible. Use of intravaginal clotrimazole, intravaginal paromomycin, intravaginal furazolidone, povidone-iodine douches, and oral nitazoxanide were unsuccessful in eradicating the patient's T. vaginalis infection. A 2-month course of intravaginal topical boric acid subsequently achieved a complete symptomatic cure and the patient remained T. vaginalis wet prep- and culture-negative 60 days after treatment.

摘要

本报告描述了一名有症状的阴道毛滴虫感染患者,该患者因严重过敏而无法耐受硝基咪唑类药物,且无法进行脱敏治疗。使用阴道克霉唑、阴道巴龙霉素、阴道呋喃唑酮、聚维酮碘灌洗以及口服硝唑尼特均未能根除该患者的阴道毛滴虫感染。随后,为期2个月的阴道局部硼酸疗程实现了症状完全治愈,且患者在治疗60天后阴道毛滴虫湿片镜检和培养均为阴性。

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