Skuta R, Danaj M, Duda I, Dobrovodský A
Chirurgická klinika FN Trnava a FZSP Trnavskej Univerzity.
Rozhl Chir. 2012 Apr;91(4):246-8.
The McKittrick-Wheelock syndrome is a very rare complication of rectal villous adenoma, characterized by fluid and electrolyte hypersecretion from a rectal tumour, which can lead to acute renal failure. We present a case review of a 67-year-old male patient hospitalised for profuse secretory diarrhea, with electrolyte dysbalance and progressive renal failure. A rectoscopic finding of massive rectal adenoma contributed to establishing the correct diagnosis. Resection of the affected part of the rectum resulted in rapid restoration from mineral imbalance and improvement of renal functions. The reported case shows the necessity of interdisciplinar management and the importance of surgical treatment in patients with this rare diagnosis.
麦基特里克-惠洛克综合征是直肠绒毛状腺瘤一种非常罕见的并发症,其特征是直肠肿瘤导致液体和电解质分泌过多,可引发急性肾衰竭。我们对一名67岁男性患者进行了病例回顾,该患者因大量分泌性腹泻住院,伴有电解质失衡和进行性肾衰竭。直肠镜检查发现巨大直肠腺瘤有助于明确诊断。切除直肠病变部位后,矿物质失衡迅速得到纠正,肾功能也有所改善。该病例报告显示了跨学科管理的必要性以及手术治疗对于这种罕见诊断患者的重要性。