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[根据免疫组化黏蛋白和CD10表达对胃癌进行分型]

[Variants of gastric carcinomas according to immunohistochemical mucins and CD10 expressions].

作者信息

Gaganov L E, Kazantseva I A, Gurevich L E, Korsakova N A

出版信息

Arkh Patol. 2012 Mar-Apr;74(2):3-5.

PMID:22880404
Abstract

Mucins and glycoprotein CD10 expression in 55 carcinomas of the stomach has been studied by immunohistochemistry. According to a profile of mucins and CD10 expression, 3 immunophenotypic variants of carcinoma were founded: gastric, intestinal and gastro-intestinal. Gastric and gastro-intestinal variants were more frequently than intestinal one. The correlation between the expression of investigated markers and histological type of carcinoma wasn't revealed The estimation of Ki-67 index has shown that the highest proliferative activity (>20%) in carcinomas with gastric phenotype has been found more often than in gastro-intestinal ones.

摘要

通过免疫组织化学研究了55例胃癌中黏蛋白和糖蛋白CD10的表达。根据黏蛋白和CD10的表达情况,发现了3种癌的免疫表型变体:胃型、肠型和胃肠型。胃型和胃肠型变体比肠型更常见。未发现所研究标志物的表达与癌组织学类型之间的相关性。Ki-67指数评估显示,胃表型癌中增殖活性最高(>20%)的情况比胃肠型癌更常见。

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