Krebs L, Mortensen J
Surgical Department, Esbjerg Central Hospital, University of Aarhus, Denmark.
Urol Int. 1990;45(6):317-20. doi: 10.1159/000281728.
The long-term constancy of the pressure-flow relationship of the upper urinary tract of the pig was studied in 8 pyeloureteral units and the short-term constancy in 10 units. No constancy was found for neither pelvic baseline pressure nor for pelvic perfusion pressure with an interval of 10 weeks. Pelvic pressure is a very unstable parameter with time but variating within the normal range. Contrarily, a good constancy was found for both baseline and perfusion pressure when 3 consecutive pressure-flow procedures performed with an interval of 30 min were compared to each other. It is concluded that the short-term constancy of the pressure-flow relationship may allow in vivo investigations of the function--if any--of drugs upon the pyeloureter.
在8个肾盂输尿管单位中研究了猪上尿路压力-流量关系的长期稳定性,并在10个单位中研究了短期稳定性。在间隔10周的情况下,肾盂基线压力和肾盂灌注压力均未发现稳定性。肾盂压力随时间是一个非常不稳定的参数,但在正常范围内变化。相反,当比较间隔30分钟进行的3次连续压力-流量程序时,基线压力和灌注压力均发现有良好的稳定性。得出的结论是,压力-流量关系的短期稳定性可能允许对药物对肾盂输尿管的功能(如果有的话)进行体内研究。