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[弥漫性毒性甲状腺肿患者术前准备中离散式血浆置换方案的选择]

[The choice of a program of discrete plasmapheresis in the preoperative preparation of patients with diffuse toxic goiter].

作者信息

Neĭmark M I, Merkulov I V

出版信息

Anesteziol Reanimatol. 1990 Sep-Oct(5):62-5.

PMID:2288432
Abstract

The state of circulation and its impact on the nature of hemodynamic response during discrete plasmapheresis has been studied in 91 patients with hyperthyroidism. It has been established that the nature of cardio- and hemodynamics depends on the severity of the disease and the cardiac rhythm. In patients with mild hyperthyroidism the volume of single blood exfusion (BE) should not exceed 800 ml of blood and plasma should be replaced by colloid and crystalloid preparations in the ratio of 1:1. In patients with severe hyperthyroidism and normal cardiac rhythm the volume of single exfusion should not exceed 600 ml and plasma should be replaced by cryoplasma. In patients with severe hyperthyroidism and atrial fibrillation blood exfusion should be limited to 400 ml of blood. Simultaneously with blood exfusion it is expedient to perform cryoplasma infusion. Glycerol trinitrate and calcium antagonists may be used to prevent pulmonary hypertension.

摘要

对91例甲状腺功能亢进患者进行了研究,观察了单次血浆置换过程中的循环状态及其对血液动力学反应性质的影响。已确定心脏和血液动力学的性质取决于疾病的严重程度和心律。轻度甲状腺功能亢进患者单次放血量(BE)不应超过800毫升血液,血浆应以1:1的比例用胶体和晶体制剂替代。重度甲状腺功能亢进且心律正常的患者单次放血量不应超过600毫升,血浆应以冷沉淀替代。重度甲状腺功能亢进且伴有心房颤动的患者放血量应限制在400毫升血液。在放血的同时,进行冷沉淀输注是适宜的。可使用硝酸甘油和钙拮抗剂预防肺动脉高压。

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