Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawaii, Honolulu, HI 96822, USA.
Toxicon. 2012 Nov;60(6):1166-70. doi: 10.1016/j.toxicon.2012.07.014. Epub 2012 Aug 4.
"Snails can kill" is a statement that receives much disbelief. Yet the venom from Conus geographus, as delivered by a disposable hypodermic-like needle, has indeed killed many unsuspecting human victims. Our understanding of their milked venom the essence of these fatalities, is in itself non-existent. Here, we present the molecular mass analysis of the milked venom of C. geographus, providing the first insight into the composition of its deadly cocktail.
“蜗牛能杀人”这种说法令人难以置信。然而,圆锥蜗牛科的 Conus geographus 产生的毒液,通过一次性类似皮下注射器的注射针注入人体后,确实已经导致许多毫无防备的人类受害者死亡。对于这些致命毒液的本质,我们对其进行挤奶得到的毒液几乎一无所知。在这里,我们呈现了对 C. geographus 挤奶毒液的分子量分析,首次深入了解其致命鸡尾酒的组成。