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分析芋螺的致命鸡尾酒——芋螺科毒汁。

Analysis of a cone snail's killer cocktail--the milked venom of Conus geographus.

机构信息

Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawaii, Honolulu, HI 96822, USA.

出版信息

Toxicon. 2012 Nov;60(6):1166-70. doi: 10.1016/j.toxicon.2012.07.014. Epub 2012 Aug 4.

Abstract

"Snails can kill" is a statement that receives much disbelief. Yet the venom from Conus geographus, as delivered by a disposable hypodermic-like needle, has indeed killed many unsuspecting human victims. Our understanding of their milked venom the essence of these fatalities, is in itself non-existent. Here, we present the molecular mass analysis of the milked venom of C. geographus, providing the first insight into the composition of its deadly cocktail.

摘要

“蜗牛能杀人”这种说法令人难以置信。然而,圆锥蜗牛科的 Conus geographus 产生的毒液,通过一次性类似皮下注射器的注射针注入人体后,确实已经导致许多毫无防备的人类受害者死亡。对于这些致命毒液的本质,我们对其进行挤奶得到的毒液几乎一无所知。在这里,我们呈现了对 C. geographus 挤奶毒液的分子量分析,首次深入了解其致命鸡尾酒的组成。

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