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一个阿尔及利亚家庭四代人中出现多指畸形,其中一名个体的掌指关系多变。

Polydactyly in four generations of an Algerian family with variable metacarpo-phalangeal relationship in an individual.

作者信息

Sinha A K, Verma R S

机构信息

Department of Orthopedic Surgery, Long Island College Hospital, Suny Health Science Center, Brooklyn.

出版信息

Ann Genet. 1990;33(3):159-61.

PMID:2288461
Abstract

We report an Algerian family in which four generations show polydactyly with variable numbers of metacarpals and phalanges. The extraordinary rearrangements of the metacarpals and phalanges shown in the X-rays are most unusual. The family is highly consanguineous. The mode of inheritance appears to be dominant with reduced penetrance and variable expression.

摘要

我们报告了一个阿尔及利亚家族,其中四代人都表现出多指畸形,掌骨和指骨数量各异。X 光片中显示的掌骨和指骨的异常重排非常罕见。这个家族近亲结婚程度很高。遗传方式似乎是显性遗传,但外显率降低且表现度可变。

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