Kurpisz M
Institute of Human Genetics, Polish Academy of Sciences, Pozhán.
Arch Immunol Ther Exp (Warsz). 1990;38(1-2):61-78.
Some new information on the sperm and seminal plasma antigens which can induce responses which decrease fertility has been obtained. This recent development has not, however, brought the understanding of the subject to a stage where the production of a contraceptive antisperm vaccine for the female can be discussed realistically. Many laboratories are continuing the active investigation of the potentials of zona pellucida antigens for contraceptive approach. Also, passive immunization with human monoclonal antibodies promises to be an effective and safe method for short-term contraception and early pregnancy termination.
已获得一些关于精子和精浆抗原的新信息，这些抗原可引发降低生育能力的反应。然而，这一最新进展尚未使对该主题的理解达到能够切实讨论为女性生产避孕抗精子疫苗的阶段。许多实验室正在继续积极研究透明带抗原在避孕方法方面的潜力。此外，用人单克隆抗体进行被动免疫有望成为一种有效且安全的短期避孕和早期终止妊娠的方法。
