Wang Hai, Liu Qiaoyu, Wang Zhaoming, Zhang Feng, Li Xiangcheng, Wang Xuehao
Department of General Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, 210029, China.
J Huazhong Univ Sci Technolog Med Sci. 2012 Aug;32(4):598-600. doi: 10.1007/s11596-012-1003-9. Epub 2012 Aug 11.
The effectiveness of liver autotransplantation for patients with partial hepatic alveolar echinococcosis was analyzed. We retrospectively studied 6 patients with hepatic alveolar echinococcosis who underwent liver autotransplantation in our hospital from 2008 to 2010. We also summarized the surgical indications of liver autotransplantation for hepatic alveolar echinococcosis and our experience in the management of postoperative complications of liver autotransplantation. Of 6 patients, 5 achieved good curative results, and one died of multiple organ failure caused by portal vein thrombosis. Main complications included postoperative bleeding, bile leak and small-for-size liver graft syndrome. Liver autotransplantation offers a new approach to cure hepatic alveolar echinococcosis with non-resectable lesions. It could be the most effective method to cure intractable hepatic alveolar echinococcosis if correct handling in operation and proper prevention of complications are performed. But the long-term outcomes are still needed to be confirmed in longer follow-up.
分析了肝自体移植治疗部分肝泡型包虫病患者的疗效。我们回顾性研究了2008年至2010年在我院接受肝自体移植的6例肝泡型包虫病患者。我们还总结了肝泡型包虫病肝自体移植的手术指征以及我们在肝自体移植术后并发症处理方面的经验。6例患者中,5例取得了良好的治疗效果,1例死于门静脉血栓形成导致的多器官功能衰竭。主要并发症包括术后出血、胆漏和小肝移植综合征。肝自体移植为治疗不可切除病变的肝泡型包虫病提供了一种新方法。如果手术操作正确并适当预防并发症,它可能是治疗难治性肝泡型包虫病最有效的方法。但长期疗效仍需更长时间的随访来证实。