Department of Pharmacology and Toxicology, School of Pharmacy, An-Najoah National University Nablus, Palestine.
East Mediterr Health J. 2012 Jun;18(6):641-7. doi: 10.26719/2012.18.6.641.
This study compared the utilization and cost of antibacterial agents in surgical units of 2 government hospitals in Palestine. The consumption and cost of drugs was estimated in the units over a 1-month period in 2010 using the anatomical therapeutic chemical classification and defined daily doses (DDD) per 100 bed-days. The total consumption of antibacterial agents was 414.1 DDD and 591.5 DDD at Thabet and Rafidia hospitals respectively. These corresponded to 133.6 DDD/100 bed-days and 162.2 DDD/100 bed-days respectively, figures that were higher than those reported in surgical units in many other countries. Total cost of antibacterial agents during the study period was 24 800 and 23481 NIS for Rafidia and Thabet hospitals respectively. Approximately 11.2% and 18.0% of the total antibiotic DDD in Rafidia and Thabet hospitals were given to patients with clean surgeries in which antibiotic prophylaxis is not indicated.
本研究比较了巴勒斯坦 2 家政府医院外科病房中抗菌药物的使用和费用。2010 年,在一个月的时间内,采用解剖治疗化学分类和每 100 个床位日的限定日剂量(DDD),对这些单位的药物消耗和费用进行了估计。塔贝特医院和拉菲迪亚医院的抗菌药物总消耗量分别为 414.1 DDD 和 591.5 DDD。这相当于分别为 133.6 DDD/100 个床位日和 162.2 DDD/100 个床位日,这些数字高于许多其他国家外科病房报告的数字。在研究期间,拉菲迪亚医院和塔贝特医院的抗菌药物总费用分别为 24800 新谢克尔和 23481 新谢克尔。拉菲迪亚医院和塔贝特医院的抗生素 DDD 总量中,约有 11.2%和 18.0%用于清洁手术患者,这些患者并不需要预防性使用抗生素。