转移性激素瘤型神经内分泌癌在 68Ga-DOTANOC 生长抑素受体 PET/CT 上表现为“超级扫描”。

Metastatic neuroendocrine carcinoma presenting as a "Superscan" on 68Ga-DOTANOC somatostatin receptor PET/CT.

机构信息

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Nucl Med. 2012 Sep;37(9):892-4. doi: 10.1097/RLU.0b013e31825b1e6c.

Abstract

PET/CT imaging using Ga-labeled somatostatin analogs has become a popular noninvasive diagnostic modality in the workup of patients with neuroendocrine tumors. A 65-year-old man with pancreatic neuroendocrine tumor with confirmed liver metastases on conventional imaging underwent restaging Ga-DOTANOC PET/CT to monitor response to cold octreotide therapy. Previous PET/CT had shown presence of multiple liver and skeletal metastases along with a primary pancreatic tumor showing intense tracer uptake. The present PET/CT study showed an increase in number and uptake of the metastatic lesions suggestive of progressive disease resulting in the appearance of a superscan.

摘要

使用 Ga 标记的生长抑素类似物进行 PET/CT 成像已成为神经内分泌肿瘤患者检查中的一种流行的无创诊断方式。一名 65 岁男性患有胰腺神经内分泌肿瘤，常规影像学检查证实存在肝转移，进行 Ga-DOTANOC PET/CT 再分期以监测对冷奥曲肽治疗的反应。先前的 PET/CT 显示存在多个肝和骨骼转移，以及原发性胰腺肿瘤显示强烈的示踪剂摄取。本次 PET/CT 研究显示转移病灶的数量和摄取增加，提示疾病进展，导致出现超级扫描。