镓 68 标记 DOTANOC PET/CT 探测到生长抑素受体表达的双侧卵巢转移。

Somatostatin receptor expressing bilateral ovarian metastases detected by (68)Ga DOTANOC PET/CT.

机构信息

From the Departments of *Nuclear Medicine and PET, and †Pathology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Nucl Med. 2015 Jun;40(6):496-8. doi: 10.1097/RLU.0000000000000646.

DOI:10.1097/RLU.0000000000000646

PMID:25546200

Abstract

Bilateral ovarian metastasis from neuroendocrine tumor (NET) is uncommon. Ovarian NET could be primary or metastatic, and if it is bilateral, then the chances of metastatic disease are from 88% to 94%. Proper identification and appropriate management become necessary in such patients. Somatostatin receptor imaging by Ga-labeled DOTANOC ([1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide) PET/CT can be used for localization, staging, and restaging of NET, and it also has an impact on appropriate clinical management of patients with NET. We present here a case of somatostatin receptor expressing bilateral ovarian metastases from NET demonstrated by Ga DOTANOC PET/CT imaging.

摘要

双侧卵巢神经内分泌肿瘤（NET）转移并不常见。卵巢 NET 可以是原发性的也可以是转移性的，如果是双侧，那么转移疾病的可能性为 88%至 94%。在这些患者中，需要正确识别和适当管理。使用 Ga 标记的 DOTANOC ([1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸]-1-NaI3-奥曲肽）PET/CT 进行生长抑素受体成像可用于 NET 的定位、分期和再分期，并且对 NET 患者的适当临床管理也有影响。我们在此介绍一例通过 Ga DOTANOC PET/CT 成像显示的表达生长抑素受体的双侧卵巢 NET 转移病例。