Tubman T R, Halliday H L, McMaster D
Neonatal Intensive Care Unit, Royal Maternity Hospital, Belfast, UK.
Biol Neonate. 1990;58(6):305-10. doi: 10.1159/000243284.
Glutathione peroxidase (GPX) and selenium are important in the prevention of cellular oxidant damage. Whole-blood GPX and plasma selenium were measured at birth and sequentially afterwards in 75 preterm babies. GPX activity at birth was 2.74 +/- 0.08 (mean +/- SEM) U/ml. Mean GPX activity remained relatively unchanged for up to 70 days postnatal age. Plasma selenium at birth was 0.43 +/- 0.02 (mean +/- SEM) mumol/l), decreasing to low levels by 10 weeks postnatal age. Neither GPX activity nor plasma selenium was related to birth weight, gestational age or infant sex.
谷胱甘肽过氧化物酶（GPX）和硒在预防细胞氧化损伤方面很重要。对75名早产儿出生时及随后连续进行全血GPX和血浆硒的测量。出生时GPX活性为2.74±0.08（均值±标准误）U/ml。出生后至70日龄，平均GPX活性相对保持不变。出生时血浆硒为0.43±0.02（均值±标准误）μmol/l，至出生后10周降至低水平。GPX活性和血浆硒均与出生体重、胎龄或婴儿性别无关。
