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手术切除联合化疗成功治疗巨大原发性心脏淋巴瘤 1 例报告

Successful treatment of a large primary cardiac lymphoma by surgical resection combined with chemotherapy: report of a case.

机构信息

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.

出版信息

Surg Today. 2013 Sep;43(9):1066-70. doi: 10.1007/s00595-012-0273-y. Epub 2012 Aug 14.

Abstract

Primary cardiac lymphoma (PCL) is a rare tumor for which no treatment strategy has yet been established. This report presents the case of a large PCL that was successfully treated by emergency surgical resection combined with postoperative chemotherapy. A 60-year-old male was referred because of dyspnea on effort. Echocardiography and computed tomography scans revealed a 10 cm tumor in the right ventricle and right atrium. The tumor was suspected to be malignant because positron emission tomography/computed tomography showed a high uptake at the tumor site. The tumor was large enough to cause life-threatening obstruction, and cardiologists were therefore reluctant to perform a percutaneous biopsy. The patient underwent emergency resection. The postoperative course was satisfactory, and the diagnosis of diffuse large B cell lymphoma (DLBCL) was thus confirmed. The patient achieved complete remission after being treated with chemotherapy for DLBCL. He was alive 1 year after surgery, without any signs of recurrence.

摘要

原发性心脏淋巴瘤(PCL)是一种罕见的肿瘤,目前尚未确定其治疗策略。本报告介绍了一例成功治疗的巨大 PCL 病例,该病例采用紧急手术切除联合术后化疗。一名 60 岁男性因劳力性呼吸困难被转介。超声心动图和计算机断层扫描显示右心室和右心房有一个 10 厘米的肿瘤。正电子发射断层扫描/计算机断层扫描显示肿瘤部位摄取量高,因此怀疑肿瘤为恶性。肿瘤足够大,导致危及生命的阻塞,因此心脏病专家不愿意进行经皮活检。患者接受了紧急切除。术后情况令人满意,因此确诊为弥漫性大 B 细胞淋巴瘤(DLBCL)。该患者接受 DLBCL 化疗后达到完全缓解。手术后 1 年,患者仍然存活,无复发迹象。

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