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原发性心脏恶性淋巴瘤采用紧急心脏手术和化疗联合治疗成功。

Successful combined treatment of primary cardiac malignant lymphoma with urgent cardiac operation and chemotherapy.

作者信息

Fujita Yasufumi, Ikebuchi Masahiko, Tarui Suguru, Irie Hiroyuki

机构信息

Department of Cardiovascular Surgery, Chikamori Hospital Heart Center, Kochi, Japan.

出版信息

Circ J. 2009 May;73(5):967-9. doi: 10.1253/circj.cj-08-0064. Epub 2008 Dec 16.

DOI:10.1253/circj.cj-08-0064
PMID:19088397
Abstract

A 56-year-old man, suffering from rapidly worsening general fatigue, dyspnea on exercise and epigastralgia, was referred for evaluation and treatment of a cardiac tumor. Transthoracic echocardiography showed a 6-cm large mass occupying both the right ventricle and atrium. Gallium scintigraphy showed high uptake in the tumor site. Lymphoma was highly suggested. Urgent operation was performed and as much tumor and thrombus were removed as possible. The postoperative course was good, with cessation of right heart failure. Pathological examination suggested malignant lymphoma, diffuse large B-cell type. The patient was treated with rituximab, cyclophosphamide, Adriamycin, vincristine, and prednisone (CHOP-R) postoperatively and has survived for 2 years without signs of recurrence.

摘要

一名56岁男性,因全身乏力迅速加重、运动时呼吸困难和上腹部疼痛,被转诊以评估和治疗心脏肿瘤。经胸超声心动图显示一个6厘米大的肿块占据右心室和右心房。镓扫描显示肿瘤部位摄取高。高度怀疑为淋巴瘤。进行了紧急手术,尽可能多地切除了肿瘤和血栓。术后病程良好,右心衰竭停止。病理检查提示为恶性淋巴瘤,弥漫大B细胞型。患者术后接受了利妥昔单抗、环磷酰胺、阿霉素、长春新碱和泼尼松(CHOP-R)治疗,已存活2年,无复发迹象。

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