异丙肾上腺素和奎尼丁用于平息 Brugada 室颤风暴。
Isoprenaline and quinidine to calm Brugada VF storm.
作者信息
Furniss Guy
机构信息
Cardiology Department, Torbay General Hospital, Torquay, UK.
出版信息
BMJ Case Rep. 2012 Aug 13;2012:bcr0420114156. doi: 10.1136/bcr.04.2011.4156.
Abstract
A 3-year-old man with an implanted cardioverter-defibrillator (ICD) for type 2 Brugada syndrome was admitted to coronary care unit with ventricular fibrillation electrical storm and consequent appropriate recurrent ICD shocks. The rhythm did not settle with conventional antiarrhythmics such as β-blockers and amiodarone. An isoprenaline infusion was set up with immediate stabilisation of rhythm. After a period of monitoring, the infusion was stopped and oral quinidine was started. He has remained free of problems for 1 year. This case-report summarises these novel treatments for electrical storm in Brugada syndrome and the mechanism behind them.
摘要
一名因2型Brugada综合征植入心脏复律除颤器（ICD）的3岁男性因室颤电风暴及随后多次适当的ICD电击而入住冠心病监护病房。使用β受体阻滞剂和胺碘酮等传统抗心律失常药物未能使心律稳定。开始静脉输注异丙肾上腺素后心律立即稳定。经过一段时间的监测后，停止输注并开始口服奎尼丁。他在1年内未再出现问题。本病例报告总结了这些针对Brugada综合征电风暴的新治疗方法及其背后的机制。
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本文引用的文献
1
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Europace. 2009 May;11(5):665-6. doi: 10.1093/europace/eup070. Epub 2009 Apr 3.
2
Electrical storms in Brugada syndrome successfully treated with isoproterenol infusion and quinidine orally.
Neth Heart J. 2007;15(4):151-5. doi: 10.1007/BF03085972.
3
Efficacy of quinidine in high-risk patients with Brugada syndrome.
Circulation. 2004 Sep 28;110(13):1731-7. doi: 10.1161/01.CIR.0000143159.30585.90. Epub 2004 Sep 20.
4
Electrical storm in Brugada syndrome successfully treated using isoprenaline.
Europace. 2004 Mar;6(2):130-3. doi: 10.1016/j.eupc.2003.11.009.
5
Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation.
Circulation. 1999 Oct 12;100(15):1660-6. doi: 10.1161/01.cir.100.15.1660.
6
"Brugada" syndrome: clinical data and suggested pathophysiological mechanism.
Circulation. 1999 Feb 9;99(5):666-73. doi: 10.1161/01.cir.99.5.666.
7
Idiopathic ventricular fibrillation: inducibility and beneficial effects of class I antiarrhythmic agents.
Circulation. 1987 Apr;75(4):809-16. doi: 10.1161/01.cir.75.4.809.
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