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本文引用的文献

1
Electrical storm in Brugada syndrome successfully treated with orciprenaline; effect of low-dose quinidine on the electrocardiogram.用间羟异丙肾上腺素成功治疗Brugada综合征电风暴；低剂量奎尼丁对心电图的影响
Europace. 2009 May;11(5):665-6. doi: 10.1093/europace/eup070. Epub 2009 Apr 3.
2
Electrical storms in Brugada syndrome successfully treated with isoproterenol infusion and quinidine orally.Brugada 综合征伴电风暴患者经异丙肾上腺素静脉滴注和奎尼丁口服治疗成功。
Neth Heart J. 2007;15(4):151-5. doi: 10.1007/BF03085972.
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Efficacy of quinidine in high-risk patients with Brugada syndrome.奎尼丁在Brugada综合征高危患者中的疗效。
Circulation. 2004 Sep 28;110(13):1731-7. doi: 10.1161/01.CIR.0000143159.30585.90. Epub 2004 Sep 20.
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Electrical storm in Brugada syndrome successfully treated using isoprenaline.使用异丙肾上腺素成功治疗Brugada综合征电风暴。
Europace. 2004 Mar;6(2):130-3. doi: 10.1016/j.eupc.2003.11.009.
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Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation.Brugada综合征的细胞基础及与ST段抬高相关的其他心律失常发生机制
Circulation. 1999 Oct 12;100(15):1660-6. doi: 10.1161/01.cir.100.15.1660.
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"Brugada" syndrome: clinical data and suggested pathophysiological mechanism.“布加迪”综合征：临床数据及推测的病理生理机制
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异丙肾上腺素和奎尼丁用于平息 Brugada 室颤风暴。

Isoprenaline and quinidine to calm Brugada VF storm.

作者信息

Furniss Guy

机构信息

Cardiology Department, Torbay General Hospital, Torquay, UK.

出版信息

BMJ Case Rep. 2012 Aug 13;2012:bcr0420114156. doi: 10.1136/bcr.04.2011.4156.

DOI:10.1136/bcr.04.2011.4156
PMID:22891011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3433527/
Abstract

A 3-year-old man with an implanted cardioverter-defibrillator (ICD) for type 2 Brugada syndrome was admitted to coronary care unit with ventricular fibrillation electrical storm and consequent appropriate recurrent ICD shocks. The rhythm did not settle with conventional antiarrhythmics such as β-blockers and amiodarone. An isoprenaline infusion was set up with immediate stabilisation of rhythm. After a period of monitoring, the infusion was stopped and oral quinidine was started. He has remained free of problems for 1 year. This case-report summarises these novel treatments for electrical storm in Brugada syndrome and the mechanism behind them.

摘要

一名因2型Brugada综合征植入心脏复律除颤器（ICD）的3岁男性因室颤电风暴及随后多次适当的ICD电击而入住冠心病监护病房。使用β受体阻滞剂和胺碘酮等传统抗心律失常药物未能使心律稳定。开始静脉输注异丙肾上腺素后心律立即稳定。经过一段时间的监测后，停止输注并开始口服奎尼丁。他在1年内未再出现问题。本病例报告总结了这些针对Brugada综合征电风暴的新治疗方法及其背后的机制。