利妥昔单抗治疗后发生的嗜二氧化碳噬纤维菌血症
Capnocytophaga bacteraemia following rituximab treatment.
作者信息
Pokroy-Shapira Elisheva, Shiber Shachaf, Molad Yair
机构信息
Beilinson, Petach Tikva, Israel.
出版信息
BMJ Case Rep. 2012 Aug 13;2012:bcr2012006224. doi: 10.1136/bcr-2012-006224.
Abstract
A case is presented of Capnocytophaga bacteraemia, in a juvenile chronic arthritis (JCA) patient receiving steroids, methotrexate and rituximab. This Gram-negative bacillus commonly found in dog saliva has been described to cause illness in immune compromised hosts such as oncology patients, those receiving cytotoxic or biological drugs, alcoholics or postsplenectomy. To the best of our knowledge, this is the first report of Capnocytophaga bacteraemia following rituximab treatment.
摘要
本文报告了一例接受类固醇、甲氨蝶呤和利妥昔单抗治疗的青少年慢性关节炎（JCA）患者发生二氧化碳嗜纤维菌血症的病例。这种常见于犬类唾液中的革兰氏阴性杆菌已被描述为可在免疫功能低下的宿主中致病，如肿瘤患者、接受细胞毒性或生物药物治疗的患者、酗酒者或脾切除术后患者。据我们所知，这是利妥昔单抗治疗后发生二氧化碳嗜纤维菌血症的首例报告。
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