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颅脑损伤后哪些患者需要进行神经内分泌评估,何时以及如何评估?

Which patient requires neuroendocrine assessment following traumatic brain injury, when and how?

机构信息

Division of Neuro-endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland.

出版信息

Clin Endocrinol (Oxf). 2013 Jan;78(1):17-20. doi: 10.1111/cen.12010.

DOI:10.1111/cen.12010
PMID:22891644
Abstract

Traumatic brain injury (TBI) is an important public health problem, particularly among young adults in industrialized countries. Hypopituitarism is a common occurrence among survivors of TBI and may contribute to the associated morbidity seen in the acute and chronic phases following injury. The available data suggest that survivors of moderate to severe TBI should undergo screening for hypopituitarism particularly in the first year after injury. This requires a close liaison between endocrinologists, neurosurgeons, neuropsychologists, intensive care and rehabilitation physicians. Patients who suffer milder forms of TBI should also be considered for endocrine evaluation if they exhibit any clinical features of pituitary hormone deficiencies.

摘要

创伤性脑损伤(TBI)是一个重要的公共卫生问题,特别是在工业化国家的年轻人中。垂体功能减退症是 TBI 幸存者中常见的现象,可能导致损伤后急性和慢性阶段的相关发病率增加。现有数据表明,中度至重度 TBI 幸存者,特别是在受伤后一年,应进行垂体功能减退症筛查。这需要内分泌学家、神经外科医生、神经心理学家、重症监护和康复医生之间密切合作。如果轻度 TBI 患者表现出任何垂体激素缺乏的临床特征,也应考虑进行内分泌评估。

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