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风湿病学与肿瘤学:恶性肿瘤的风湿性表现及抗肿瘤治疗的最新综述

Rheumatology and oncology: an updated review of rheumatic manifestations of malignancy and anti-neoplastictherapy.

作者信息

Alias Abie, Rodriguez Ernesto J, Bateman Helen E, Sterrett Ashley G, Valeriano-Marcet Joanne

机构信息

Department of Rheumatology, University of South Florida, Tampa, Florida 33612, USA.

出版信息

Bull NYU Hosp Jt Dis. 2012;70(2):109-14.

Abstract

OBJECTIVE

Review of the literature addressing the rheumatic manifestations of various malignancies as well as of common chemotherapeutic agents.

METHODS

A literature search was performed to identify key articles regarding the association of rheumatic disease with malignancy.

RESULTS

Our review focused on the association of rheumatic disease with malignancy, paraneoplastic syndromes with rheumatic manifestations, and chemotherapeutic agents related to rheumatic syndromes. We have discussed the importance of a newly described autoantibody that may identify patients at risk for malignancy associated myositis.

CONCLUSION

Based on our literature review, recommendations are suggested regarding who and how patients should be screened for malignancy when presenting with various rheumatic symptoms.

摘要

目的

综述关于各种恶性肿瘤以及常用化疗药物的风湿性表现的文献。

方法

进行文献检索以确定关于风湿性疾病与恶性肿瘤关联的关键文章。

结果

我们的综述聚焦于风湿性疾病与恶性肿瘤的关联、具有风湿性表现的副肿瘤综合征以及与风湿综合征相关的化疗药物。我们讨论了一种新描述的自身抗体的重要性,该抗体可能识别出有患恶性肿瘤相关肌炎风险的患者。

结论

基于我们的文献综述,针对出现各种风湿症状的患者应由谁以及如何进行恶性肿瘤筛查提出了建议。

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