Dipartimento di Scienze Chimiche, Università di Catania, viale A. Doria 6, 95125 Catania, Italy.
J Org Chem. 2012 Sep 7;77(17):7684-7. doi: 10.1021/jo301098d. Epub 2012 Aug 22.
A pair of diastereomeric salen cavitands and their uranyl complexes combine a chiral (R,R) salen bridge and an inherent chiral tris-bridged quinoxaline cup within the same molecule. Whereas the free ligands show a preference for the same enantiomer of an α-amino acid pair, the corresponding UO(2) complexes display opposite enantiodiscrimination and exceptionally high enantioselectivities (K(D)/K(L) = 26.4).
一对非对映异构的手性大环冠醚及其铀酰配合物在同一分子内结合了手性（R,R）西佛碱桥和固有手性三桥联喹喔啉环。虽然游离配体优先与α-氨基酸对的相同对映异构体结合，但相应的 UO(2) 配合物表现出相反的对映体选择性和极高的对映体选择性（K(D)/K(L) = 26.4）。
