Department of Chemistry, Hunter College, City University of New York, NY 10065, USA.
Phytochemistry. 2012 Nov;83:168-72. doi: 10.1016/j.phytochem.2012.07.014. Epub 2012 Aug 12.
Labdanes, leonurenones A-C, two known labdanes, luteolin 7-O-β-glucoside and luteolin were isolated and characterized from a commercial source of Leonotis leonurus. Genetic methods allowed for identification of the plant material. The leonurenones contain an uncommon α,β-unsaturated enone moiety in ring B, and leonurenones A and B were evaluated in a competitive inhibition assay at the GABA A neuroreceptor site.
从商业来源的 Leonotis leonurus 中分离并鉴定了 Labdanes、leonurenones A-C、两种已知的 Labdanes、木犀草素 7-O-β-葡萄糖苷和木犀草素。遗传方法允许鉴定植物材料。Leonurenones 在环 B 中含有不常见的α,β-不饱和烯酮部分,并且在 GABA A 神经受体部位的竞争性抑制测定中评估了 leonurenones A 和 B。