Kumar Indu, Ali Kashif, Usman-Saeed Muniba, Saeed Muhammad Usman
Department of Ophthalmology, Countess of Chester, Chester, UK.
BMJ Case Rep. 2012 Aug 14;2012:bcr1220115418. doi: 10.1136/bcr.12.2011.5418.
The authors report the follow-up of a 68-year-old lady with bilateral anterior uveitis secondary to erlotinib. Erlotinib was started and stopped after symptoms and signs suggestive of severe bilateral anterior uveitis were noted. The patient developed signs of a non-ST elevation myocardial infarction, 12 days after stopping the erlotinib, and recovered without major problems. The patient also reported intermittent low-grade fever since starting erlotinib which resolved after stopping this drug. No further symptoms of uveitis were noted up to 6 month follow-up. The patient reported improved well being, resolution of ocular symptoms and intermittent low-grade fever at last follow-up (6 months after stopping erlotinib).
作者报告了一名68岁女性患者的随访情况,该患者因使用厄洛替尼继发双侧前葡萄膜炎。在注意到提示严重双侧前葡萄膜炎的症状和体征后,开始并停用了厄洛替尼。患者在停用厄洛替尼12天后出现非ST段抬高型心肌梗死的体征,并顺利康复,未出现重大问题。患者还报告自开始使用厄洛替尼以来间歇性低热,停药后症状缓解。在6个月的随访中未再出现葡萄膜炎症状。患者在最后一次随访(停用厄洛替尼6个月后)报告称身体状况改善,眼部症状消失,间歇性低热也已缓解。