Ali Kashif, Kumar Indu, Usman-Saeed Muniba, Usman Saeed Muhammad
Department of Ophthalmology, Countess of Chester Hospital, Chester, UK.
BMJ Case Rep. 2011 May 24;2011:bcr0320113988. doi: 10.1136/bcr.03.2011.3988.
The authors report the case of a 68-year-old woman with secondary adenocarcinoma of the lungs from an unknown primary. Erlotinib was started which produced symptoms suggestive of uveitis. Erlotinib was stopped and restarted a month later at a lower dose, which resulted in severe bilateral anterior uveitis. The uveitis settled after stopping erlotinib and treatment with topical steroids and cycloplegics. To the best of the authors' knowledge, this is the first case of erlotinib-related anterior uveitis.
作者报告了一例68岁女性患者,患有原发灶不明的继发性肺腺癌。开始使用厄洛替尼治疗后出现提示葡萄膜炎的症状。停用厄洛替尼,一个月后以较低剂量重新开始使用,结果导致严重的双侧前部葡萄膜炎。停用厄洛替尼并使用局部类固醇和睫状肌麻痹剂治疗后,葡萄膜炎得到缓解。据作者所知,这是首例与厄洛替尼相关的前部葡萄膜炎病例。