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[泌尿生殖道的术中冰冻切片诊断]

[Intraoperative frozen section diagnosis of the genitourinary tract].

作者信息

Bertz S, Schmitz-Dräger B J, Protzel C, Hartmann A

机构信息

Pathologisches Institut, Universitätsklinikum Erlangen, Krankenhausstr. 8-10, 91054, Erlangen, Deutschland.

出版信息

Pathologe. 2012 Sep;33(5):441-9. doi: 10.1007/s00292-012-1600-1.

DOI:10.1007/s00292-012-1600-1
PMID:22892659
Abstract

Up to now intraoperative frozen section, diagnosis has been of limited utility in urologic oncology. In the future, it may become more important due to a significant increase in the number of nerve-sparing operations performed for prostate cancer. Accuracy and benefit of intraoperative frozen sections depend both on a good communication between surgeons and pathologists as well as on a strict assessment of the need for surgery in the individual patient. In order to optimize cost-efficiency and to reduce the associated risks the indications for intraoperative frozen sections must be rigorously appraised. This report outlines clinically relevant indications for intraoperative frozen section diagnosis in tumors of the urinary tract, kidneys, prostate, testis and penis according to the most recent guidelines. The diagnostic scope and problems of this method are also discussed.

摘要

到目前为止,术中冰冻切片诊断在泌尿外科肿瘤学中的应用有限。未来,由于前列腺癌保留神经手术数量的显著增加,它可能会变得更加重要。术中冰冻切片的准确性和益处既取决于外科医生和病理学家之间的良好沟通,也取决于对个体患者手术必要性的严格评估。为了优化成本效益并降低相关风险,必须严格评估术中冰冻切片的适应证。本报告根据最新指南概述了尿路、肾脏、前列腺、睾丸和阴茎肿瘤术中冰冻切片诊断的临床相关适应证。还讨论了该方法的诊断范围和问题。

相似文献

1
[Intraoperative frozen section diagnosis of the genitourinary tract].[泌尿生殖道的术中冰冻切片诊断]
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2
[Relevance of intraoperative frozen section diagnostics in urological surgery].
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[Can the prostatic capsule be preserved during cystectomy for bladder tumors: a study of urethral and prostatic involvement in the cystectomy specimens].膀胱肿瘤膀胱切除术期间前列腺包膜能否保留:对膀胱切除标本中尿道及前列腺受累情况的研究
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本文引用的文献

1
Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and robot-assisted laparoscopic radical prostatectomy: experience after 11,069 consecutive patients.神经血管结构毗邻冷冻切片检查(NeuroSAFE)增加了在开放性和机器人辅助腹腔镜根治性前列腺切除术中保留神经的频率,并减少了阳性手术切缘:11069 例连续患者的经验。
Eur Urol. 2012 Aug;62(2):333-40. doi: 10.1016/j.eururo.2012.04.057. Epub 2012 May 10.
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Increased risk of overall and cardiovascular mortality after radical nephrectomy for renal cell carcinoma 2 cm or less.根治性肾切除术治疗 2cm 或更小的肾细胞癌后,全因和心血管死亡率增加。
J Urol. 2011 Oct;186(4):1247-53. doi: 10.1016/j.juro.2011.05.054. Epub 2011 Aug 17.
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Adenomatoid tumors of the female and male genital tract. A comparative clinicopathologic and immunohistochemical analysis of 47 cases emphasizing their site-specific morphologic diversity.女性和男性生殖道腺瘤样肿瘤。47 例强调其特定部位形态多样性的比较临床病理和免疫组织化学分析。
Virchows Arch. 2011 May;458(5):593-602. doi: 10.1007/s00428-011-1054-5. Epub 2011 Feb 20.
4
Survival benefit of radical prostatectomy in lymph node-positive patients with prostate cancer.前列腺癌淋巴结阳性患者行根治性前列腺切除术的生存获益。
Eur Urol. 2010 May;57(5):754-61. doi: 10.1016/j.eururo.2009.12.034. Epub 2010 Jan 20.
5
Good outcome for patients with few lymph node metastases after radical retropubic prostatectomy.耻骨后根治性前列腺切除术后淋巴结转移较少的患者预后良好。
Eur Urol. 2008 Aug;54(2):344-52. doi: 10.1016/j.eururo.2008.05.023. Epub 2008 May 21.
6
Immediate versus deferred androgen deprivation treatment in patients with node-positive prostate cancer after radical prostatectomy and pelvic lymphadenectomy.前列腺癌根治术和盆腔淋巴结清扫术后淋巴结阳性患者的即刻与延迟雄激素剥夺治疗
Lancet Oncol. 2006 Jun;7(6):472-9. doi: 10.1016/S1470-2045(06)70700-8.
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Dynamic sentinel node biopsy in penile carcinoma: evaluation of 10 years experience.阴茎癌的动态前哨淋巴结活检:10年经验评估
Eur Urol. 2005 May;47(5):601-6; discussion 606. doi: 10.1016/j.eururo.2004.11.018. Epub 2005 Jan 22.
8
Positive resection margins in partial penectomies: sites of involvement and proposal of local routes of spread of penile squamous cell carcinoma.阴茎部分切除术切缘阳性:受累部位及阴茎鳞状细胞癌局部扩散途径的探讨
Am J Surg Pathol. 2004 Mar;28(3):384-9. doi: 10.1097/00000478-200403000-00012.
9
Intraoperative frozen section analysis during nerve sparing laparoscopic radical prostatectomy: feasibility study.保留神经的腹腔镜根治性前列腺切除术中的术中冰冻切片分析:可行性研究。
J Urol. 2003 Nov;170(5):1843-6. doi: 10.1097/01.ju.0000092081.71167.34.
10
Value of frozen section examination for the management of nonpalpable incidental testicular tumors.
Eur Urol. 2003 Oct;44(4):458-60. doi: 10.1016/s0302-2838(03)00316-6.