Bertz S, Schmitz-Dräger B J, Protzel C, Hartmann A
Pathologisches Institut, Universitätsklinikum Erlangen, Krankenhausstr. 8-10, 91054, Erlangen, Deutschland.
Pathologe. 2012 Sep;33(5):441-9. doi: 10.1007/s00292-012-1600-1.
Up to now intraoperative frozen section, diagnosis has been of limited utility in urologic oncology. In the future, it may become more important due to a significant increase in the number of nerve-sparing operations performed for prostate cancer. Accuracy and benefit of intraoperative frozen sections depend both on a good communication between surgeons and pathologists as well as on a strict assessment of the need for surgery in the individual patient. In order to optimize cost-efficiency and to reduce the associated risks the indications for intraoperative frozen sections must be rigorously appraised. This report outlines clinically relevant indications for intraoperative frozen section diagnosis in tumors of the urinary tract, kidneys, prostate, testis and penis according to the most recent guidelines. The diagnostic scope and problems of this method are also discussed.
到目前为止,术中冰冻切片诊断在泌尿外科肿瘤学中的应用有限。未来,由于前列腺癌保留神经手术数量的显著增加,它可能会变得更加重要。术中冰冻切片的准确性和益处既取决于外科医生和病理学家之间的良好沟通,也取决于对个体患者手术必要性的严格评估。为了优化成本效益并降低相关风险,必须严格评估术中冰冻切片的适应证。本报告根据最新指南概述了尿路、肾脏、前列腺、睾丸和阴茎肿瘤术中冰冻切片诊断的临床相关适应证。还讨论了该方法的诊断范围和问题。