Ribeiro Camila Ferrari, Siqueira Elisa Beatriz Dalledone, Holler Ana Paula, Fabrício Lincoln, Skare Thelma Larocca
Department of Dermatology, Evangelical University Hospital of Curitiba, Evangelical College of Paraná, PR, Brazil.
An Bras Dermatol. 2012 Jul-Aug;87(4):550-3. doi: 10.1590/s0365-05962012000400005.
Nailfold capillaroscopy is a useful technique for evaluating changes in microcirculation.
To investigate changes at nailfold capillaroscopy in psoriatic patients compared with controls.
Nailfold capillaroscopy was performed in 46 psoriatic patients and 50 controls to assess microscopic morphological changes, capillary density and the presence of areas with devascularization.
Patients with psoriasis had lower capillary density (p=0.0005), increased avascular areas (p=0.0035) and an increased number of morphologically abnormal capillaries (coiled, p<0.0001) compared to controls. No association was found between capillary density and the duration of the disease (p = 0.92) or the extent of skin involvement, as measured by the psoriasis area and severity index (PASI) score (p = 0.59). The presence of avascular areas was more common in psoriatic individuals whose nails were affected by the condition (p = 0.047).
Patients with psoriasis have decreased capillary density and a greater presence of morphologically abnormal capillaries when compared to controls.
甲襞毛细血管镜检查是评估微循环变化的一项有用技术。
研究银屑病患者与对照组相比甲襞毛细血管镜检查的变化。
对46例银屑病患者和50例对照者进行甲襞毛细血管镜检查，以评估微观形态学变化、毛细血管密度及无血管区的存在情况。
与对照组相比，银屑病患者的毛细血管密度较低（p = 0.0005），无血管区增加（p = 0.0035），形态异常的毛细血管数量增加（卷曲，p < 0.0001）。未发现毛细血管密度与疾病持续时间（p = 0.92）或皮肤受累程度（通过银屑病面积和严重程度指数（PASI）评分衡量，p = 0.59）之间存在关联。无血管区在指甲受该疾病影响的银屑病个体中更常见（p = 0.047）。
与对照组相比，银屑病患者的毛细血管密度降低，形态异常的毛细血管更多见。
