The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea.

Suppr

超能文献

作者信息

Skidmore C J, Davies M I, Goodwin P M, Halldorsson H, Lewis P J, Shall S, Zia'ee A A

出版信息

Eur J Biochem. 1979 Nov 1;101(1):135-42. doi: 10.1111/j.1432-1033.1979.tb04225.x.

DOI:10.1111/j.1432-1033.1979.tb04225.x

PMID:228934

Abstract

摘要

相似文献

The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea.

Eur J Biochem. 1979 Nov 1;101(1):135-42. doi: 10.1111/j.1432-1033.1979.tb04225.x.

Participation of poly(ADP-ribosyl)ation in the depression of RNA synthesis caused by treatment of mouse lymphoma cells with methylnitrosourea.聚（ADP - 核糖基）化在甲基亚硝基脲处理小鼠淋巴瘤细胞所致RNA合成抑制中的作用。

J Biol Chem. 1982 Apr 25;257(8):4027-30.

Poly (ADP-ribose) metabolism in alkylated mouse L5178Y cells.烷基化小鼠L5178Y细胞中的聚（ADP-核糖）代谢

Carcinogenesis. 1985 Jul;6(7):1005-9. doi: 10.1093/carcin/6.7.1005.

Effect of carcinogenic N-alkyl-N-nitroso compounds on nicotinamide adenine dinucleotide metabolism.致癌性N-烷基-N-亚硝基化合物对烟酰胺腺嘌呤二核苷酸代谢的影响。

Cancer Res. 1980 Jun;40(6):1797-802.

Effect of 1-methyl-1-nitrosourea on poly(adenosine diphosphate-ribose) polymerase activity at the nucleosomal level.1-甲基-1-亚硝基脲对核小体水平聚（二磷酸腺苷核糖）聚合酶活性的影响。

Cancer Res. 1979 Apr;39(4):1405-10.

Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitroso-urea. Further evidence for the involvement of (ADP-ribose)n in DNA repair.

FEBS Lett. 1981 Aug 17;131(1):173-7. doi: 10.1016/0014-5793(81)80913-1.

The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of gamma-radiation by inhibitors of poly(ADP-ribose) polymerase.聚（ADP-核糖）聚合酶抑制剂增强N-甲基-N-亚硝基脲和γ射线的细胞毒性

Eur J Biochem. 1980 Apr;105(3):525-30. doi: 10.1111/j.1432-1033.1980.tb04528.x.

Acceptors for the poly ADP-ribosylation modification of chromatin structure are altered by carcinogen-induced DNA damage.致癌物诱导的DNA损伤会改变染色质结构聚ADP核糖基化修饰的受体。

Carcinogenesis. 1982;3(10):1143-8. doi: 10.1093/carcin/3.10.1143.

Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity.亚硝基脲与染色质的相互作用及其对聚（二磷酸腺苷核糖）聚合酶活性的影响。

Cancer Res. 1979 Apr;39(4):1411-7.

(ADP-ribose)n participates in DNA excision repair.（ADP - 核糖）n参与DNA切除修复。

Nature. 1980 Feb 7;283(5747):593-6. doi: 10.1038/283593a0.

引用本文的文献

A comprehensive review of immunotherapy in gastrointestinal tumors with a focus on the role of combination therapy with PARP inhibitors.胃肠道肿瘤免疫治疗的全面综述，重点关注与PARP抑制剂联合治疗的作用。

Naunyn Schmiedebergs Arch Pharmacol. 2025 Jun 9. doi: 10.1007/s00210-025-04336-z.

Antioxidant Defenses and Poly(ADP-Ribose) Polymerase (PARP) Activity Provide "Radioresilience" Against Ionizing Radiation-Induced Stress in Dwarf Bean Plants.抗氧化防御和聚（ADP-核糖）聚合酶（PARP）活性为矮生菜豆植物提供抵御电离辐射诱导应激的“辐射抗性”。

Antioxidants (Basel). 2025 Feb 25;14(3):261. doi: 10.3390/antiox14030261.

Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models.溃疡性结肠炎中NAD+代谢与免疫细胞浸润之间的相互作用：亚型鉴定及新型诊断模型的开发

Front Immunol. 2025 Feb 5;16:1479421. doi: 10.3389/fimmu.2025.1479421. eCollection 2025.

1,25-Dihydroxyvitamin D Suppresses UV-Induced Poly(ADP-Ribose) Levels in Primary Human Keratinocytes, as Detected by a Novel Whole-Cell ELISA.1,25-二羟维生素 D 通过新型全细胞 ELISA 检测抑制原代人角质形成细胞中 UV 诱导的多聚（ADP-核糖）水平。

Int J Mol Sci. 2024 May 21;25(11):5583. doi: 10.3390/ijms25115583.

Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.在蛭形轮虫阿迪内塔vag中，电离辐射反应似乎是脱水反应的附带现象。

BMC Biol. 2024 Jan 25;22(1):11. doi: 10.1186/s12915-023-01807-8.

NAD Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies.NAD代谢与免疫调节：炎症性肠病治疗的新方法

Antioxidants (Basel). 2023 Jun 7;12(6):1230. doi: 10.3390/antiox12061230.

A Case Study of Clinical Response to Rucaparib in a Patient with Metastatic Castration-Resistant Prostate Cancer and a .一例转移性去势抵抗性前列腺癌和. 患者对鲁卡帕利临床反应的病例研究

Curr Oncol. 2022 Jun 8;29(6):4178-4184. doi: 10.3390/curroncol29060333.

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.抑制烟酰胺磷酸核糖转移酶（NAMPT），即烟酰胺腺嘌呤二核苷酸（NAD）补救途径的限速酶，通过线粒体氧化应激靶向神经胶质瘤异质性。

Neuro Oncol. 2022 Feb 1;24(2):229-244. doi: 10.1093/neuonc/noab175.

Role of Oxidative DNA Damage and Repair in Atrial Fibrillation and Ischemic Heart Disease.氧化DNA损伤与修复在心房颤动和缺血性心脏病中的作用

Int J Mol Sci. 2021 Apr 7;22(8):3838. doi: 10.3390/ijms22083838.

Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance.聚腺苷二磷酸核糖聚合酶抑制剂的治疗选择途径和潜在耐药机制。

Exp Mol Med. 2021 Jan;53(1):42-51. doi: 10.1038/s12276-021-00557-3. Epub 2021 Jan 25.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验