Brouns S H A, Schieveld J, Leue C
Maastricht Universitair Medisch Centrum.
Tijdschr Psychiatr. 2012;54(8):747-51.
A 17-year-old man was referred to the Med-Psych-Unit because of recurrent episodes of hypersomnia, megaphagia, hypersexual behaviour and cognitive disturbances. Over the period of three years he suffered more than 10 episodes of hypersomnia each lasting 8 to 16 days. The clinical presentation was suggestive of the Kleine-Levin syndrome. The symptoms disappeared after treatment with methylphenidate, but it was not clear whether this could be attributed to the medication or to the self-limiting character of the illness. The Kleine-Levin syndrome is often clinically not recognised due to the variation in the symptoms and the lack of objective diagnostic examination.
一名17岁男性因反复出现发作性嗜睡、贪食、性欲亢进及认知障碍而被转诊至精神医学科。在三年时间里,他经历了10余次发作性嗜睡,每次发作持续8至16天。临床表现提示为克莱恩-莱文综合征。经哌甲酯治疗后症状消失,但尚不清楚这是药物所致还是疾病的自限性特点。由于症状的多样性以及缺乏客观诊断检查,克莱恩-莱文综合征在临床上常未被识别。