Balderson Benjamin H, Grothaus Lou, Harrison Robert G, McCoy Katryna, Mahoney Christine, Catz Sheryl
Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA.
AIDS Care. 2013;25(4):451-8. doi: 10.1080/09540121.2012.712669. Epub 2012 Aug 15.
The population of persons living with HIV (PLWH) is growing older and more prone to developing other chronic health conditions. Disease progression has been shown to be related to quality of life (QoL). However, descriptions of chronic comorbid illnesses and the unique QoL challenges of older adults living with HIV are not well understood and have not been examined in multiple geographic locations. About 452 PLWH aged 50 years or older were recruited from AIDS Service Organizations in nine states. Participants completed a telephone survey that included measures of other chronic health conditions, perceived stress, depression, and health-related quality of life. As much as 94% of the sample reported a chronic health condition in addition to HIV (mode = 2). The highest reported conditions were hypertension, chronic pain, hepatitis, and arthritis. Despite relatively high rates of depression, overall QoL was moderately high for the sample. Physical functioning was most impacted by the addition of other chronic health problems. Social functioning, mental health functioning, stress, and depression were also strongly associated with chronic disease burden. Additional chronic health problems are the norm for PLWH aged 50 years and older. QoL is significantly related to the addition of chronic health problems. As increasing numbers of PLWH reach older age, this raises challenges for providing comprehensive healthcare to older PLWH with multiple chronic conditions.
感染艾滋病毒者（PLWH）的群体年龄在增长，且更容易患上其他慢性健康问题。疾病进展已被证明与生活质量（QoL）相关。然而，对于慢性合并症以及老年艾滋病毒感染者独特的生活质量挑战的描述尚未得到充分理解，且未在多个地理位置进行过研究。从九个州的艾滋病服务组织招募了约452名50岁及以上的感染艾滋病毒者。参与者完成了一项电话调查，其中包括对其他慢性健康问题、感知压力、抑郁以及与健康相关的生活质量的测量。多达94%的样本报告除艾滋病毒外还患有慢性健康问题（众数 = 2）。报告最多的疾病是高血压、慢性疼痛、肝炎和关节炎。尽管抑郁发生率相对较高，但样本的总体生活质量处于中等水平。身体功能受其他慢性健康问题的影响最大。社会功能、心理健康功能、压力和抑郁也与慢性病负担密切相关。对于50岁及以上的感染艾滋病毒者来说，额外的慢性健康问题是常态。生活质量与慢性健康问题的增加显著相关。随着越来越多的感染艾滋病毒者步入老年，这给为患有多种慢性病的老年感染艾滋病毒者提供全面医疗保健带来了挑战。
