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[用于失血性休克复苏的全血输注:吉布提的两例病例]

[Whole-blood transfusion for hemorrhagic shock resuscitation: two cases in Djibouti].

作者信息

Cordier P Y, Eve O, Dehan C, Topin F, Menguy P, Bertani A, Massoure P L, Kaiser E

机构信息

Département d'Anesthésie-Réanimation-Urgences, Service d'Anesthésie-Réanimation, Hôpital d'Instruction des Armées Laveran, Marseille, France.

出版信息

Med Sante Trop. 2012 Apr-Jun;22(2):213-6. doi: 10.1684/mst.2012.0056.

Abstract

Hemorrhagic shock requires early aggressive treatment, including transfusion of packed red blood cells and hemostatic resuscitation. In austere environments, when component therapy is not available, warm fresh whole-blood transfusion is a convenient treatment. It provides red blood cells, clotting factors, and functional platelets. Therefore it is commonly used in military practice to treat hemorrhagic shock in combat casualties. At Bouffard Hospital Center in Djibouti, the supply of packed red blood cells is limited, and apheresis platelets are unavailable. We used whole blood transfusion in two civilian patients with life-threatening non-traumatic hemorrhages. One had massive bleeding caused by disseminated intravascular coagulation due to septic shock; the second was a 39 year-old pregnant woman with uterine rupture. In both cases, whole blood transfusion (twelve and ten 500 mL bags respectively), combined with etiological treatment, enabled coagulopathy correction, hemorrhage control, and satisfactory recovery.

摘要

失血性休克需要早期积极治疗,包括输注浓缩红细胞和进行止血复苏。在资源匮乏的环境中,当无法进行成分输血时,输注温热的新鲜全血是一种便捷的治疗方法。它能提供红细胞、凝血因子和有功能的血小板。因此,它在军事实践中常用于治疗战斗伤员的失血性休克。在吉布提的布法尔医院中心,浓缩红细胞的供应有限,且无法获得单采血小板。我们对两名患有危及生命的非创伤性出血的平民患者使用了全血输血。其中一名患者因感染性休克导致弥散性血管内凝血而出现大量出血;另一名是一名39岁的孕妇,发生了子宫破裂。在这两例病例中,全血输血(分别为12袋和10袋500毫升),结合病因治疗,实现了凝血功能障碍的纠正、出血的控制以及令人满意的康复。

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