New light on p27(kip1) in breast cancer.
作者信息
Belletti Barbara, Baldassarre Gustavo
出版信息
Cell Cycle. 2012 Oct 1;11(19):3701-2. doi: 10.4161/cc.21573. Epub 2012 Aug 16.
Abstract
摘要
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New light on p27(kip1) in breast cancer.乳腺癌中p27（kip1）的新见解
Cell Cycle. 2012 Oct 1;11(19):3701-2. doi: 10.4161/cc.21573. Epub 2012 Aug 16.
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本文引用的文献
1
The landscape of cancer genes and mutational processes in breast cancer.乳腺癌中的癌症基因和突变过程景观。
Nature. 2012 May 16;486(7403):400-4. doi: 10.1038/nature11017.
2
Role of T198 modification in the regulation of p27(Kip1) protein stability and function.T198 修饰在调节 p27(Kip1) 蛋白稳定性和功能中的作用。
PLoS One. 2011 Mar 14;6(3):e17673. doi: 10.1371/journal.pone.0017673.
3
p27 as Jekyll and Hyde: regulation of cell cycle and cell motility.p27 犹如杰基尔和海德：细胞周期和细胞迁移的调节。
Cell Cycle. 2009 Nov 1;8(21):3455-61. doi: 10.4161/cc.8.21.9789. Epub 2009 Nov 11.
4
The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.p27（kip1）的肿瘤抑制功能包括对间充质/阿米巴样转变的控制。
Mol Cell Biol. 2009 Sep;29(18):5031-45. doi: 10.1128/MCB.00144-09. Epub 2009 Jul 13.
5
RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.RSK1促使p27Kip1在T198位点发生磷酸化，以促进对RhoA的抑制并增强细胞运动性。
Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9268-73. doi: 10.1073/pnas.0805057106. Epub 2009 May 22.
6
p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.p27Kip1表达抑制胶质母细胞瘤的生长、侵袭及肿瘤诱导的新生血管形成。
Mol Cancer Ther. 2008 May;7(5):1164-75. doi: 10.1158/1535-7163.MCT-07-2154.
7
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy.人类癌症中的细胞周期蛋白依赖性激酶抑制剂p27：预后潜力及与抗癌治疗的相关性
Nat Rev Cancer. 2008 Apr;8(4):253-67. doi: 10.1038/nrc2347.
8
p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.人癌症中p27（kip1）的功能调控：治疗设计的潜在靶点
Curr Med Chem. 2005;12(14):1589-605. doi: 10.2174/0929867054367149.
9
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.p27（Kip1）与微管相关蛋白stathmin的相互作用影响肉瘤细胞的迁移和侵袭。
Cancer Cell. 2005 Jan;7(1):51-63. doi: 10.1016/j.ccr.2004.11.025.
10
The murine gene p27Kip1 is haplo-insufficient for tumour suppression.小鼠基因p27Kip1在肿瘤抑制方面存在单倍体不足。
Nature. 1998 Nov 12;396(6707):177-80. doi: 10.1038/24179.
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