Department of Neurosurgery, University Hospital, Zurich, Switzerland.
J Clin Microbiol. 2012 Oct;50(10):3409-11. doi: 10.1128/JCM.00802-12. Epub 2012 Aug 15.
We report a clinical case of meningoencephalitis with subdural empyema in an immunocompromised farmer caused by toxigenic Clostridium perfringens type A, which was identified by 16S RNA gene analysis of cerebrospinal fluid and subdural empyema. In immunocompromised patients, C. perfringens should be considered a potential pathogen of sepsis.
我们报告了一例免疫功能低下农民因产毒A型产气荚膜梭菌引起的脑膜脑炎伴硬膜下积脓的临床病例,该病例通过脑脊液和硬膜下积脓的 16S RNA 基因分析鉴定。在免疫功能低下患者中,产气荚膜梭菌应被视为脓毒症的潜在病原体。