Riaz Hasan, Zaiden Robert, Khan Mohammad, Latif Naeem
University of Florida College of Medicine, Jacksonville, Florida 32209, USA.
Clin Adv Hematol Oncol. 2012 Jul;10(7):477-80.
Plasmablastic lymphoma (PBL) is listed in the World Health Organization (WHO) classification as a subtype of diffuse large B-cell lymphoma (DLBCL). Some morphologic features of PBL are similar to DLBCL; however, PBL has minimal or no expression of CD20 and leukocyte common antigen. Instead, PBL has been characterized by the plasmablastic morphology of the cancer cells, with high mitotic figures. It is believed to be an aggressive lymphoma. We describe a case of a patient who seemed to pose a diagnostic dilemma, and who was later found to have PBL.
浆母细胞淋巴瘤（PBL）在世界卫生组织（WHO）分类中被列为弥漫性大B细胞淋巴瘤（DLBCL）的一种亚型。PBL的一些形态学特征与DLBCL相似；然而，PBL的CD20和白细胞共同抗原表达极少或无表达。相反，PBL的特征是癌细胞具有浆母细胞形态，有较高的有丝分裂象。它被认为是一种侵袭性淋巴瘤。我们描述了一例看似存在诊断困境的患者，该患者后来被发现患有PBL。
