Department of Rheumatology, Unit of Translational Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan,
Mod Rheumatol. 2013 Sep;23(5):1022-8. doi: 10.1007/s10165-012-0731-9. Epub 2012 Aug 16.
A 76-year-old woman was diagnosed with chronic active Epstein-Barr virus (EBV) infection (CAEBV) with sustained fever, anemia, numbness of the lower limbs, and liver dysfunction. The patient had an unusual anti-EBV antibody profile and high viral load, positive rheumatoid factor, and cryoglobulinemia. She suffered from recurrent hemosputum with pleural effusion and thrombocytopenia caused by CAEBV infection, and she died in July 2008. Here, we present a rare case of CAEBV infection with cryoglobulinemia in an elderly patient.
一位 76 岁女性被诊断为慢性活动性 EBV 感染（CAEBV），伴有持续发热、贫血、下肢麻木和肝功能异常。该患者具有异常的 EBV 抗体谱和高病毒载量，类风湿因子阳性，伴有冷球蛋白血症。她因 CAEBV 感染反复发作咯痰伴胸腔积液和血小板减少，于 2008 年 7 月死亡。本文报道了一例老年 CAEBV 感染伴冷球蛋白血症的罕见病例。
